PROTEIN INTRINSICALLY DISORDERED REGION PREDICTION BY COMBINING NEURAL ARCHITECTURE SEARCH AND MULTI-OBJECTIVE GENETIC ALGORITHM

Protein intrinsically disordered region prediction by combining neural architecture search and multi-objective genetic algorithm

Abstract Background Intrinsically disordered regions (IDRs) are widely distributed in proteins and related to many important biological functions.Accurately identifying IDRs is of great significance for protein structure and function analysis.Because the long disordered regions (LDRs) and short disordered regions (SDRs) share different characterist

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Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment

Abstract Background Tuberculosis remains an infectious disease of global concern, with potential impacts on respiratory and intestinal microbiota owing to prolonged broad-spectrum antibiotic therapy.Despite its potential to cause infertility, the vaginal microbiota of women with genital tuberculosis remains poorly understood.We comprehensively anal

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Evaluation of hydration status calculated from differences in venous and capillary plasma dilution during stepwise crystalloid infusions: A randomized crossover study in healthy volunteers

Background and objective: A mini volume loading test (mVLT) was proposed for estimating hydration status and interstitial fluid accumulation during stepwise infusion of crystalloids.The method is based on both the transcapillary reflux model and the Fill-In Fibers hypothesis that when subjects are dehydrated, venous plasma dilution induced by a flu

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Environmental and Economic of Flooring Building Materials

Green building Harvard High Frequency HID Gear design requires use of building materials that minimize environmental impact, necessitating selection of building materials by their environmental profile as well as economic cost-benefit considerations.The objective of this research is to determine the environmental impacts per square meter of three f

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